Visiting Lecce means immersing yourself in a luminous, cultured and surprising city, often known as the City of Sun, Sea and Wind. With its golden-stone alleyways, grand piazzas and noble palaces, Lecce tells a story rich in art and culture, home to one of the most fascinating Baroque expressions in Europe.
Thanks to its historical and cultural importance, Lecce was shortlisted as a candidate for European Capital of Culture, confirming its place among the must-visit destinations in Southern Italy.

Palazzo Sant’Anna is located in the heart of Lecce’s historic centre, perfectly set among the city’s most authentic streets. Within a few minutes’ walk, guests can reach some of the most remarkable landmarks, starting with Porta Rudiae, one of the ancient entrances to the city, originally medieval and rebuilt in the 18th century.
Continuing towards the centre, you will discover the magnificent Piazza del Duomo, dominated by the Cathedral of Cattedrale di Santa Maria Assunta and its 72-metre bell tower, one of the tallest in Southern Italy.
From here, along Via Vittorio Emanuele II, you reach Piazza Sant’Oronzo, the vibrant heart of the city. This lively square is home to some of Lecce’s most iconic landmarks: the Colonna di Sant’Oronzo, the Anfiteatro Romano, the Palazzo del Seggio, and the churches of Chiesa di San Marco and Chiesa di Santa Maria delle Grazie.
Walking along Via Templari, you arrive at the celebrated Basilica di Santa Croce, an absolute masterpiece of Lecce Baroque. Its richly decorated façade, dominated by a magnificent rose window, perfectly blends Renaissance harmony with Baroque exuberance.
The itinerary can continue to the Castello di Lecce, a 16th-century fortress commissioned by Charles V, and conclude at the Villa Comunale Giuseppe Garibaldi, a beloved meeting place for locals and a peaceful green retreat also appreciated by guests of Palazzo Sant’Anna.
The property is located approximately 700 metres from Lecce railway station and 47 km from Aeroporto del Salento.Upon request, our team can arrange private transfer services.
Situated within a pedestrian area, Palazzo Sant’Anna is accessible by car for luggage drop-off. Parking is available nearby, with assistance from our staff.